palate

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Mutation associated with cleft palate in humans, dogs identified

Scientists studying birth defects in humans and purebred dogs have identified an association between cleft lip and cleft palate — conditions that occur when the lip and mouth fail to form properly during pregnancy — and a mutation in the ADAMTS20 gene. Their findings were presented at the American Society of Human Genetics (ASHG) 2014 […]

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Cleft palate discovery in dogs to aid in understanding human birth defect

UC Davis School of Veterinary Medicine researchers have identified the genetic mutation responsible for a form of cleft palate in the dog breed Nova Scotia Duck Tolling Retrievers. They hope that the discovery, which provides the first dog model for the craniofacial defect, will lead to a better understanding of cleft palate in humans. Although […]

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