A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients with leukemia. In recent years, many doctors have shelved 6-TG in exchange for newer drugs that are more effective. Now, Jeffrey Bryan, an associate professor of oncology at the MU College of Veterinary Medicine, and his colleagues found that 6-TG can not only kill cancer cells, but also works to change how certain cancer cells function, weakening those cells so they can be killed by other drugs.
Every cell in the body has certain genetic characteristics called epigenetic markers that give cells instructions on how to act, when to multiply and when to die. Cancer cells often have epigenetic markers that cause genes to be either turned off or out of control. This causes those cells to grow rapidly, become difficult to kill and ultimately damage the body. When testing the drug on cells from dogs with cancer, the MU researchers found that 6-TG can affect these epigenetic markers in cancer cells through a chemical process called demethylation. This process works to turn off damaging epigenetic markers and turn on markers that make the cells act in a healthy manner. Bryan says this discovery could lead to future cancer treatments using multiple drugs to fight the disease from different sides.
“While 6-TG is no longer one of the more powerful cancer-killing drugs doctors have at their disposal, we found that it could still be useful to fight cancer in conjunction with other drugs,” said Bryan, who also is the director of the Comparative Oncology and Epigenetics Laboratory
… Continue reading here.
Dogs News — Sciencedaily
https://www.youtube.com/watch?v=4PmElYD5pMc&fs=1&rel=0
These dogs make the best babysitters. They can make babies stop crying with their singing!
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Credits
Videos:
https://www.youtube.com/watch?v=peeJHsO6ACk
https://www.youtube.com/watch?v=v8qT1ngJDKs
https://www.youtube.com/watch?v=rdVo1ikBoJA
Song:
“All Fall Down” via Purple Planet Music
http://www.purple-planet.com/royalty-free-music/
Grreat Choice Uncracked Pig Dog Toy
This Easter, get crackin’! Crack open one of our Grreat Choice Plush Pig Inside a Pink Egg and enjoy some interactive fun with your favorite furry friend. The bunny is detailed with a plush exterior and an internal squeaker for added fun. Only at PetSmart. Features: Internal squeaker for added fun Includes: 1 Plush Pig Inside a Pink Egg Intended For: Dogs Activity: Cuddling, squeaking fun! Color: Pink Material: Polyester Fibers, Plastic Egg and Squeaker Cleaning Instructions: Hand wash with pet-safe detergent. Warning: Ingestion of this product can result in serious injury. Observe your pet’s behavior with the toy for suitability. Some toys may be inappropriate for your pet. Remove and replace the toy if it becomes damaged.
Price: $ 1.47
Sold by PetSmart
Proof That #Dogs Make The Best #Babysitters
they just hate the high tones of the crying
Como que tendrémos comprar uno para Kristelita
Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!
Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!
Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!
Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!
UN NUOVO CANTATE O UNA BRAVA BABY SITTER …DECIDETE VOI …MA SONO
STUPENDI…
UN FELICE MERCOLEDÌ A TUTTI!
Proof That Dogs Make The Best Babysitters: http://youtu.be/4PmElYD5pMc
Sono e saranno sempre la passione della mia vita…i bambini e gli
animali!!!! <3
Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!
Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!
Incredibileee! Buonanotte
Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!