Old cancer drug could have new use in fighting cancer

A used for decades to treat leukemia may have other uses in the fight against , researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cells in patients with leukemia. In recent years, many doctors have shelved 6-TG in exchange for newer drugs that are more effective. Now, , an associate professor of oncology at the , and his colleagues found that 6-TG can not only kill , but also works to change how certain cancer cells function, weakening those cells so they can be killed by other drugs.

Every cell in the body has certain genetic characteristics called epigenetic markers that give cells instructions on how to act, when to multiply and when to die. Cancer cells often have epigenetic markers that cause genes to be either turned off or out of control. This causes those cells to grow rapidly, become difficult to kill and ultimately damage the body. When testing the on cells from with cancer, the MU researchers found that 6-TG can affect these epigenetic markers in cancer cells through a chemical process called demethylation. This process works to turn off damaging epigenetic markers and turn on markers that make the cells act in a healthy manner. Bryan says this discovery lead to future cancer treatments using multiple drugs to fight the disease from different sides.

“While 6-TG is no longer one of the more powerful cancer-killing drugs doctors have at their disposal, we found that it still be useful to fight cancer in conjunction with other drugs,” said Bryan, who also is the director of the Comparative Oncology and Epigenetics Laboratory

… Continue reading here.
Dogs News — Sciencedaily


https://www.youtube.com/watch?v=4PmElYD5pMc&fs=1&rel=0

These make the best babysitters. They can make babies stop crying with their singing!

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Credits
Videos:
https://www.youtube.com/watch?v=peeJHsO6ACk

https://www.youtube.com/watch?v=v8qT1ngJDKs
https://www.youtube.com/watch?v=rdVo1ikBoJA


Song:
“All Fall Down” via Purple Planet Music
http://www.purple-planet.com/royalty-free-music/

Grreat Choice Uncracked Pig Dog Toy


This Easter, get crackin’! Crack open one of our Grreat Choice Plush Pig Inside a Pink Egg and enjoy some interactive fun with your favorite furry friend. The bunny is detailed with a plush exterior and an internal squeaker for added fun. Only at PetSmart. Features: Internal squeaker for added fun Includes: 1 Plush Pig Inside a Pink Egg Intended For: Dogs Activity: Cuddling, squeaking fun! Color: Pink Material: Polyester Fibers, Plastic Egg and Squeaker Cleaning Instructions: Hand wash with pet-safe detergent. Warning: Ingestion of this product can result in serious injury. Observe your pet’s behavior with the toy for suitability. Some toys may be inappropriate for your pet. Remove and replace the toy if it becomes damaged.

Price: $ 1.47
Sold by PetSmart


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Comments

    • Madamnesia
    • April 3, 2015

    Proof That #Dogs Make The Best #Babysitters

    • Willem Pie
    • April 3, 2015

    they just hate the high tones of the crying 

    • ROSSANA MORALES DE LARRAZABAL
    • April 3, 2015

    Como que tendrémos comprar uno para Kristelita

    • Fabiana Rodrigues
    • April 3, 2015

    Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!

    • roselaine rocha
    • April 3, 2015

    Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!

    • Fabiana Rodrigues
    • April 3, 2015

    Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!

    • Ira Pereira
    • April 3, 2015

    Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!

    • Giovann Giovanni
    • April 3, 2015

    UN NUOVO CANTATE O UNA BRAVA BABY SITTER …DECIDETE VOI …MA SONO
    STUPENDI…

    UN FELICE MERCOLEDÌ A TUTTI!

    Proof That Dogs Make The Best Babysitters: http://youtu.be/4PmElYD5pMc

    • stefis72
    • April 3, 2015

    Sono e saranno sempre la passione della mia vita…i bambini e gli
    animali!!!! <3

    • Clau Rusch
    • April 3, 2015

    Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!

    • regina maria tardin
    • April 3, 2015

    Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!

    • luca ribotta
    • April 3, 2015

    Incredibileee! Buonanotte

    • Patricia De Biase
    • April 3, 2015

    Uma Criança Está Fazendo Birra, Mas Veja Como O Cão Age … SENSACIONAL!

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