Veterinarians use nanoparticles to deliver cancer treatment in dogs, cats

Veterinarians use nanoparticles to deliver cancer treatment in dogs, cats

When Michael and Sandra Friedlander first came to the three years ago with their dog, Grayton, they learned some bad news: Grayton had nasal adenocarcinoma, a form of with a short life expectancy.

“Most with this form of cancer are with their owners no more than a few months after the diagnosis, but here Grayton is three years later,” said Michael Friedlander, who is the executive director of the and senior dean at the Carilion School of Medicine.

No stranger to medical research, Friedlander was referred by Veterinary Teaching Hospital clinicians to an experimentalAbout Dogs at the University of Florida called , which delivers precise, high dosages of radiation to a tumor and can only be performed once.

“That shrunk the tumor down to almost nothing,” said Friedlander, who is also the associate provost for health sciences at Virginia Tech. “We knew when Grayton had the procedure that we couldn’t do it again, but now the cancer is back.”

Today, the 11-year-old Labradoodle is the first patient at the Virginia-Maryland College of Veterinary Medicine in a new clinical trial that is testing the use of and a targeted for solid tumors in dogs and . The study is one of several on new treatments for client-owned companion animals at the college. In January, the college established the Veterinary Clinical Research Office to help facilitate this work.

“Clinical research at the veterinary college involves both primary research focused on advancing the treatment and diagnosis of veterinary diseases and translational research in which spontaneous diseases in animals can be used as models of human disease,” said Dr. Greg Daniel, head of the Department of Small Animal Clinical Sciences. “In the latter situation, we can provide our companion animal patients with treatment and diagnostic options that are not yet available in mainstream human medicine.”

Although medical researchers have tested gold nanoparticles with targeted laser treatments on human patients with some success, the treatment is still new to both human and veterinary medicine. The college is one of four current veterinary schools around the country testing the AuroLase therapy developed by Nanospectra Biosciences Inc., a startup company based in Houston, Texas. The others are Texas A&M University, the University of Wisconsin-Madison, and the University of Georgia.

Dr. Nick Dervisis, assistant professor of oncology in the Department of Small Animal Clinical Sciences, is leading the Nanospectra-funded study. Following a rhinoscopy performed on Grayton by Dr. David Grant, associate professor of internal medicine, Dervisis began the one-time, experimental therapy.

“The treatment involves two phases,” Dervisis said. “First, we infuse the patient with the gold nanoparticles. Although the nanoparticles distribute throughout the body, they tend to concentrate around blood vessels associated with tumors. Within 36 hours, they have cleared the bloodstream except for tumors.

… Continue reading here.
Dogs News — Sciencedaily

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Comments

    • Terra Plays!
    • August 14, 2014

    Running out of ideas.

    • A Nurwhal
    • August 14, 2014

    These dogs are more useful than me…

    • Brock Gosselin
    • August 14, 2014

    Anyone else thought they meant breeds of dogs?

    • Snivy Terphione
    • August 14, 2014

    Why do people always compare cats and dogs? =_= Personally I like sloths.

    • Savi™
    • August 14, 2014

    This is amazingly adorable and intelligent beings.

    This proves all animals are as smart as humans.

    • Juliana W.Q.
    • August 14, 2014

    I want a dog :(

    • Calikid331
    • August 14, 2014

    This proves why dogs are better than cats. cats are just…. scary

    • Namilea LOTI
    • August 14, 2014

    Omg the bike riding dog!

    • Dean Rudes
    • August 14, 2014

    WOAH.

    • Adam Ramadan
    • August 14, 2014

    How is that painting? He’s literally moving a brush in his mouth

    • TinCanMan47
    • August 14, 2014

    I bet a cat cant ride a bike. Your move cats.

    • TheJelliCopter
    • August 14, 2014

    Dogs rule cats drool… Except dogs drool and it’s adorable. Cats just
    suck.

    • Jordan King
    • August 14, 2014

    That’s all cool and everything, but.. what’s the point in teaching a dog to
    ride a bike?

    • bryn jones
    • August 14, 2014

    I believe all
    Dog can do anything

    • JustAnotherSunny
    • August 14, 2014

    Painting is not the same as moving a brush on a paper..

    • Equoise
    • August 14, 2014

    Yeah, if you want dog saliva over all your stuff… :/

    • my names not rick
    • August 14, 2014

    this is cruel and inhumane

    • mmuu9966
    • August 14, 2014

    Cats are better than dogs anyway, so this video was shit.

    • Immajeanyus
    • August 13, 2014

    Mmm. Love the taste of dog kisses with my waffles.

    • Jaafar Farhan
    • August 13, 2014

    I still don’t believe that those dogs actually exist. Prove if BuzzFeed.

    • HenrySims
    • August 13, 2014

    Wait, why 9 dogs? Couldn’t be 10? Such an odd number to do a list.

    • martin knudsen
    • August 13, 2014

    what about the one dog that learned how to drive a car

    • FC12Carter12
    • August 13, 2014

    I wish I had a dog that made breakfast for me

    • PressFartToContinue
    • August 13, 2014

    That dog who could paint was the most impressive.
    11/10 would breed

    • BuzzFeedVideo
    • August 13, 2014

    Which dog was your favorite?

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