Cheaper, more efficient method for detecting leishmaniosis developed

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Leishmaniosis is a mostly afflicting dogs, but in impoverished countries it affects over 12 million humans, of whom 70,000 lose their lives every year. Researchers from the LeishmanCeres Group at the have a new of the illness in animals, based on a single hair sample and only one analysis, which saves cost, time and healthcare personnel.

For the last 25 years, the LeishmanCeres research group at the (UEx) has been studying the detection and analysis of leishmaniosis. This parasitic disease affects 12 million people a year, most of whom are in poor countries, and 70,000 of whom die from it.

The main sufferers of this disease are dogs, in whom it can also be fatal. However, it has also been detected in , who can be carriers.

The scientists from the UEx have produced a study, published in the journal Acta Tropica, in which they describe a new technique that detects the disease in the hair of wild mammals using a single fur sample and only one analysis known as a qPCR.

As Rubén Muñoz Madrid, the main author of the study, tells SINC: “This new method saves a significant amount of money, time and human resources when compared with current combined methods of diagnosis.”

The usual diagnostic techniques for leishmaniosis in always combine several very costly methods of achieving sensitive, reliable results.

“On the one hand, we have parasitological techniques such as microscopic observation of the parasite or DNA amplification which use tissue samples — from blood that is not very sensitive, liver, spleen or bone marrow — and on the other, immunological methods for specific antibodies in blood using indirect immunofluorescence (IIF) or ELISA enzyme-linked immunosorbent assay,” the researcher explains.

The fox, one of the main carriers in Europe

The epidemiological studies conducted in Europe on leishmaniosis (France, Portugal and Spain) confirm that the fox (Vulpes vulpes) is one of the major wild reservoirs of the disease. Prevalence rates are very variable but are high, varying between 5% and 75% according to the authors.

The wolf (Canis lupus) is a far less significant wild reservoir due to its low prevalence (0-5%). “Foxes and various species of rodents according to habitat are responsible for the maintenance of wild leishmaniosis,” the expert adds.

It is still too early for scientists to know the scope of this new method based on fur, as they have only been able to confirm the presence of parasitic DNA in hair on dogs, and laboratory mouse infected with a species of Leishmania major, the cause of cutaneous leishmaniosis in humans in Europe, Asia and Africa.

“We believe that these results are sufficient to demonstrate that the hair of different species of mammal behaves as a tissue to sequester and

… Continue reading here.
Dogs News — Sciencedaily

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    • James Warrum
    • February 24, 2014

    Who DOESN’T LOVE laughing babies?!!?!

    • katapo777
    • February 24, 2014

    the two best things in the whole world

    • VeneratioDiaboli
    • February 24, 2014

    Whats wrong with 314 people???

    • Olivia Tom
    • February 24, 2014

    Does anyone know the breed of the huge,black,fluffy dog getting hosed by
    the baby.

    • nince021
    • February 24, 2014

    The kid at 0:30-0:40 has got the best laugh!

    • Christelle Larocque
    • February 24, 2014

    What is the type of dog at 4:40?

    • Jenny Munns
    • February 24, 2014


    • Gfury2000
    • February 24, 2014

    How I wish that I found dogs this amusing.

    • Baoyue Yau
    • February 24, 2014


    • Juan Johnson
    • February 24, 2014

    348 were not loved when children

    • Insane A
    • February 24, 2014

    Lmao XD

    • Kitty Girl
    • February 24, 2014

    6:05 OMG SOOOO UTE <3

    • José Luis Gordillo T.
    • February 24, 2014


    • dishfun99
    • February 24, 2014


    • srijita chakraborty
    • February 24, 2014

    Cute monkey

    • Tajaldeen Wahab
    • February 24, 2014

    how did i get here from airsoft gun reveiws

    • neida camacho
    • February 24, 2014

    4:14 is so cute haha the dog wasn’t even doing anything!

    • fin38
    • February 24, 2014

    0:48 The baby is learning team work

    • S Hodge
    • February 24, 2014

    I don’t see how people can hut either of God’s two greatest creations. If
    found guilty of harming either they should be shot within ten minutes.

    • Nono lae
    • February 24, 2014

    5:15 that dog is HUGE!

    • sunny19886
    • February 24, 2014

    5.15 thought it was a bear XD

    • BlackAliceRose7
    • February 24, 2014

    That laugh is contagious <3

    • Elise Renae
    • February 24, 2014


    • Catty Hopeflyte
    • February 24, 2014

    dog: WHAT ZA F*CK IZ GOING ON?!?!?!?! HELP!!!!

    • Shelly Ray
    • February 24, 2014

    I remember my son’s first laugh.

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